Phenotypes Associated with This Genotype

Genotype
MGI:6358156

• Allelic Composition: Magi1^{Gt(OST33326)Lex}/Magi1⁺
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

respiratory system

abnormal lung endothelial cell physiology ( J:278456 )

• lung endothelial cells exposed to disturbed blood flow and laminar blood flow showed less activation evidenced by markedly decreased anti-VCAM-1 staining

• Body size and weight, development, life span, and organ structures at the gross anatomic levelife span, and organ structures at the gross anatomic level are indistinguishable compaired to the control mice.

• blood pressure was normotensive

• normal plasma IL-6 level

• the inflammatory response of isolated peripheral blood mononuclear cells (PBMCs), bone marrow-derived macrophages (BMDMs), splenocytes, and vascular smooth muscle cells (VSMCs) were nomal