Phenotypes for Set Trp53 MGI:6357935 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Set^tm1.1Wgu/Set^tm1.1Wgu Trp53^tm1Tyj/Trp53^tm1Tyj
Genetic Background	involves: 129S2/SvPas * 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Set^tm1.1Wgu mutation (0 available); any Set mutation (46 available)
Trp53^tm1Tyj mutation (12 available); any Trp53 mutation (236 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:276962 )

• while no viable double homozygous mice are seen at birth, viable and morphologically normal double homozygous mice are found at E11.5 and E13.5 indicating a delay in lethality compared to mice homozygous for Set^tm1.1Wgu alone

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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