Phenotypes for Atp6ap2 Tg(Six2-EGFP/cre)1Amc MGI:6357740 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Atp6ap2^tm1.1Aich/Atp6ap2⁺ Tg(Six2-EGFP/cre)1Amc/0
Genetic Background	involves: C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp6ap2^tm1.1Aich mutation (0 available); any Atp6ap2 mutation (11 available)
Tg(Six2-EGFP/cre)1Amc mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

albuminuria ( J:228872 )

• increase in urinary albumin excretion

glomerulosclerosis ( J:228872 )

• focal glomerulosclerosis

decreased kidney weight ( J:228872 )

• kidney weight is reduced at 2 months of age

homeostasis/metabolism

increased circulating creatinine level ( J:228872 )

albuminuria ( J:228872 )

• increase in urinary albumin excretion

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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