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Phenotypes Associated with This Genotype
Genotype
MGI:6357719
Allelic
Composition		 Mapkapk2tm1.1Gkl/Mapkapk2tm1.1Gkl
Tg(Tie1-cre)9Ref/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapkapk2tm1.1Gkl mutation (1 available); any Mapkapk2 mutation (33 available)
Tg(Tie1-cre)9Ref mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased incidence of tumors by chemical induction ( J:262876 )
• smaller tumors induced by AOM/DSS
• however, development of induced colitis is normal

neoplasm
decreased incidence of tumors by chemical induction ( J:262876 )
• smaller tumors induced by AOM/DSS
• however, development of induced colitis is normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory