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Phenotypes Associated with This Genotype
Genotype
MGI:6331079
Allelic
Composition		 Pik3r4mbe/Pik3r4tm1.1Mpnd
Emx1tm1(cre)Krj/Emx1+
Genetic
Background		 involves: 129S2/SvPas * C3H/HeH * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1(cre)Krj mutation (2 available); any Emx1 mutation (31 available)
Pik3r4mbe mutation (0 available); any Pik3r4 mutation (64 available)
Pik3r4tm1.1Mpnd mutation (2 available); any Pik3r4 mutation (64 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal hippocampus pyramidal cell layer ( J:258027 )
• pyramidal cell layer is fractured
ectopic hippocampus pyramidal cells ( J:258027 )
• increase in the number of ectopic pyramidal cells in the stratum oriens layer
abnormal hippocampus stratum oriens morphology ( J:258027 )
• the stratum oriens layer contains ectopic pyramidal cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/09/2026
MGI 6.24 		The Jackson Laboratory