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Phenotypes Associated with This Genotype
Genotype
MGI:6317342
Allelic
Composition
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pparatm1Gonz/Pparatm1Gonz
Genetic
Background
involves: 129 * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm1.1Pcha mutation (0 available); any Pkd1 mutation (153 available)
Pparatm1Gonz mutation (5 available); any Ppara mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• cyst epithelial proliferation is increased
• all mice exhibit numerous kidney cysts
• kidney-weight to body-weight ratio is increased

cellular
• cyst epithelial proliferation is increased

growth/size/body
• all mice exhibit numerous kidney cysts
• kidney-weight to body-weight ratio is increased


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory