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Phenotypes Associated with This Genotype
Genotype
MGI:6307806
Allelic
Composition
2210010C04Riktm1.1Satom/2210010C04Rik+
Genetic
Background
B6(FVB)-2210010C04Riktm1.1Satom
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No mouse lines available in IMSR.
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phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• variable size at 4 to 5 weeks of age
• however, size at 2 to 3 weeks is normal
• beginning at 4 weeks of age
• replaced with adipose in late chronic pancreatitis
• somewhat in late chronic pancreatitis
• in some mice at 4 to 5 weeks of age due to edema
• at 2 months of age
• in half of mice at 4 to 5 weeks of age
• in most mice at 2, 6 and 12 months of age
• in late chronic pancreatitis
• starting at 3 weeks and more frequently at 4 to 5 weeks of age with edema, infiltration of neutrophil granulocytes and macrophages, and widespread evidence of regeneration
• starting at 2 months and continuing through 6 and 12 months with adipose replacement proceeding to late chronic pancreatitis

homeostasis/metabolism
N
• mice exhibit normal blood glucose at 12 months of age
• at 4 to 5 weeks of age

digestive/alimentary system
• beginning at 4 weeks of age
• replaced with adipose in late chronic pancreatitis

immune system
• starting at 3 weeks and more frequently at 4 to 5 weeks of age with edema, infiltration of neutrophil granulocytes and macrophages, and widespread evidence of regeneration
• starting at 2 months and continuing through 6 and 12 months with adipose replacement proceeding to late chronic pancreatitis

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
pancreatitis DOID:4989 OMIM:167800
J:267764


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory