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Phenotypes Associated with This Genotype
Genotype
MGI:6285774
Allelic
Composition		 PtprcM10Btlr/PtprcM10Btlr
Genetic
Background		 C57BL/6J-PtprcM10Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
PtprcM10Btlr mutation (0 available); any Ptprc mutation (209 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B-1b cell number ( J:272777 )
• reduced frequencies of B1b cells in B1 cells in the peripheral blood
decreased IgE level ( J:272777 )
• reduced circulating levels of total IgE

hematopoietic system
decreased B-1b cell number ( J:272777 )
• reduced frequencies of B1b cells in B1 cells in the peripheral blood
decreased IgE level ( J:272777 )
• reduced circulating levels of total IgE

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory