Analysis Tools
growth/size/body
nervous system
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• at 19 days of age only 20.2% of normal levels of Npy+ soma are present in the arcuate nucleus, the Npy+ cell bodies are clustered aberrantly within and adjacent to the median eminence, and lack Npy+ processes that normally extend towards and into the paraventricular nucleus or dorsomedial nucleus of the hypothalamus
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hematopoietic system
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• platelets from homozygotes appear smaller and 17.5% contain large vacuoles, although electron microscopy shows only normal morphology and numbers of dense and alpha granules
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• after activation with thrombin, platelets from homozygotes have decreased levels of P-selectin on the surface compared with heterozgyous or wildtype controls
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homeostasis/metabolism
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• after activation with thrombin, platelets from homozygotes have decreased levels of P-selectin on the surface compared with heterozgyous or wildtype controls
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