Phenotypes Associated with This Genotype

Genotype
MGI:6276338

• Allelic Composition: Tg(CAG-Ncoa6)104Hwl/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

dilated cardiomyopathy ( J:269856 )

cardiovascular system

cardiac hypertrophy ( J:80609 )

dilated cardiomyopathy ( J:269856 )

abnormal impulse conducting system conduction ( J:80609 )

• mice exhibit conduction defects

endocrine/exocrine glands

abnormal adrenal gland morphology ( J:80609 )

• adrenal gland redness

abnormal pituitary gland morphology ( J:80609 )

• pituitary gland redness and swelling

thymus atrophy ( J:80609 )

dilated gallbladder ( J:80609 )

• gall bladder hydrops

hematopoietic system

thymus atrophy ( J:80609 )

spleen atrophy ( J:80609 )

homeostasis/metabolism

abnormal atrial thrombosis ( J:80609 )

• mice exhibit atrial thrombosis

immune system

thymus atrophy ( J:80609 )

spleen atrophy ( J:80609 )

liver/biliary system

dilated gallbladder ( J:80609 )

• gall bladder hydrops

hepatic steatosis ( J:80609 )

nervous system

abnormal pituitary gland morphology ( J:80609 )

• pituitary gland redness and swelling

renal/urinary system

renal hypoplasia ( J:80609 )

vision/eye

cataract ( J:80609 )

• adults exhibit unilateral cataracts

microphthalmia ( J:80609 )

• adults exhibit unilateral microphthalmia

growth/size/body

cardiac hypertrophy ( J:80609 )