Phenotypes Associated with This Genotype

Genotype
MGI:6263058

• Allelic Composition: Nucks1^{tm1b(EUCOMM)Hmgu}/Nucks1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Nucks1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0682_5_E06

Data Sources

IMPC Data for Nucks1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - HMGU

digestive/alimentary system

abnormal jejunum morphology ( J:211773 )

♂

IMPC - HMGU

abnormal stomach morphology ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

increased leukocyte cell number ( J:211773 )

♂

IMPC - HMGU

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

♀

IMPC - HMGU

decreased circulating glucose level ( J:211773 )

♀

IMPC - HMGU

decreased circulating triglyceride level ( J:211773 )

IMPC - HMGU

decreased circulating chloride level ( J:211773 )

♀

IMPC - HMGU

immune system

increased leukocyte cell number ( J:211773 )

♂

IMPC - HMGU

enlarged lymph nodes ( J:211773 )

♂

IMPC - HMGU

integument

abnormal vibrissa morphology ( J:211773 )

IMPC - HMGU

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - HMGU

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - HMGU

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - HMGU