Phenotypes Associated with This Genotype

Genotype
MGI:6262153

• Allelic Composition: Clcnkb^em1(IMPC)Mbp/Clcnkb^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Clcnkb^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Clcnkb

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - UCD

behavior/neurological

increased grip strength ( J:211773 )

IMPC - UCD

decreased locomotor activity ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - UCD

abnormal heart shape ( J:211773 )

♀

IMPC - UCD

enlarged heart ( J:211773 )

IMPC - UCD

small heart ( J:211773 )

IMPC - UCD

decreased heart weight ( J:211773 )

IMPC - UCD

shortened QRS complex duration ( J:211773 )

♀

IMPC - UCD

shortened QT interval ( J:211773 )

IMPC - UCD

digestive/alimentary system

abnormal stomach morphology ( J:211773 )

♀

IMPC - UCD

endocrine/exocrine glands

abnormal pancreas morphology ( J:211773 )

♀

IMPC - UCD

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

IMPC - UCD

increased lean body mass ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

enlarged urinary bladder ( J:211773 )

IMPC - UCD

enlarged liver ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

increased basophil cell number ( J:211773 )

♀

IMPC - UCD

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - UCD

decreased mean corpuscular volume ( J:211773 )

IMPC - UCD

increased red blood cell distribution width ( J:211773 )

♂

IMPC - UCD

increased neutrophil cell number ( J:211773 )

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - UCD

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

IMPC - UCD

increased fasting circulating glucose level ( J:211773 )

IMPC - UCD

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - UCD

increased blood urea nitrogen level ( J:211773 )

IMPC - UCD

improved glucose tolerance ( J:211773 )

IMPC - UCD

abnormal cholesterol homeostasis ( J:211773 )

♀

IMPC - UCD

increased circulating cholesterol level ( J:211773 )

♀

IMPC - UCD

immune system

increased basophil cell number ( J:211773 )

♀

IMPC - UCD

increased neutrophil cell number ( J:211773 )

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - UCD

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

IMPC - UCD

enlarged lymph nodes ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - UCD

enlarged liver ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

abnormal urinary bladder morphology ( J:211773 )

IMPC - UCD

enlarged urinary bladder ( J:211773 )

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

skeleton

abnormal bone structure ( J:211773 )

IMPC - UCD