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Phenotypes Associated with This Genotype
Genotype
MGI:6260011
Allelic
Composition		 Rps6tm1Gtho/Rps6+
Trp53tm1Tyj/Trp53tm1Tyj
Tg(KRT5-cre)5132Jlj/0
Genetic
Background		 involves: 129 * C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rps6tm1Gtho mutation (3 available); any Rps6 mutation (15 available)
Tg(KRT5-cre)5132Jlj mutation (1 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (249 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
pigmentation phenotype ( J:139244 )
N
• mice exhibit normal footpad pigmentation and normal Kitl mRNA levels in the footpad epidermis at P30, indicating complete reversal of the phenotype observed in mice that are only heterozygous for Rps6tm1Gtho and hemizygous for Tg(KRT5-cre)5132Jlj

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory