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Phenotypes Associated with This Genotype
Genotype
MGI:6246531
Allelic
Composition		 Flgtm1Amag/Flgtm1Amag
Tg(CD207-Dta)312Dhka/0
Genetic
Background		 involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flgtm1Amag mutation (2 available); any Flg mutation (42 available)
Tg(CD207-Dta)312Dhka mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased inflammatory response ( J:229771 )
• Th17 and gammadeltaT17 responses induced by topical S. aureus inoculation are abrogated, indicating that Langerhans cells mediate IL-17 responses against S. aureus

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory