Phenotypes for Gt(ROSA)26Sor Tg(Pdgfra-cre/ERT)467Dbe MGI:6197799 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm1(Smo/EYFP)Amc}/Gt(ROSA)26Sor⁺ Tg(Pdgfra-cre/ERT)467Dbe/0
Genetic Background	involves: 129X1/SvJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(Smo/EYFP)Amc} mutation (1 available); any Gt(ROSA)26Sor mutation (942 available)
Tg(Pdgfra-cre/ERT)467Dbe mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

respiratory system

abnormal pulmonary alveolus morphology ( J:264185 )

• tamoxifen-treated mice show reduced density of alveoli

overexpanded pulmonary alveolus ( J:264185 )

• alveoli are enlarged in tamoxifen-treated mice

emphysema ( J:264185 )

• tamoxifen-treated mice exhibit emphysematous changes including enlarged alveoli with reduced alveolar density

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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