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Phenotypes Associated with This Genotype
Genotype
MGI:6196862
Allelic
Composition		 Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Tg(Itgax-cre)1-1Reiz/0
Genetic
Background		 involves: C3H * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Itgax-cre)1-1Reiz mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body size ( J:260047 )
• mice are runted

hematopoietic system
increased neutrophil cell number ( J:260047 )
• mice exhibit elevation of neutrophils in tissues
increased monocyte cell number ( J:260047 )
• mice exhibit elevation of monocytes in tissues

immune system
increased neutrophil cell number ( J:260047 )
• mice exhibit elevation of neutrophils in tissues
increased monocyte cell number ( J:260047 )
• mice exhibit elevation of monocytes in tissues

skeleton
skeleton phenotype ( J:260047 )
N
• mice do not develop joint swellings

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory