Phenotypes Associated with This Genotype

Genotype
MGI:6163718

• Allelic Composition: Adam10^Pied/Adam10^Pied; Hr^hr/Hr^hr
• Genetic Background: involves: CAST/EiJ * HRA/SkhKcl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:262499 )

• no mice are present at weaning

embryo

small pharyngeal arch ( J:262499 )

• at E9.5

caudal body truncation ( J:262499 )

• at E9.5

decreased embryo size ( J:262499 )

• at E9.5

abnormal neural tube morphology ( J:262499 )

• irregularly shaped at E9.5

abnormal somite border morphology ( J:262499 )

• not delineated at E9.5

cardiovascular system

abnormal heart looping ( J:262499 )

• linear at E9.5

enlarged pericardium ( J:262499 )

• at E9.5

nervous system

abnormal neural tube morphology ( J:262499 )

• irregularly shaped at E9.5

telencephalon hypoplasia ( J:262499 )

• at E9.5

growth/size/body

decreased embryo size ( J:262499 )

• at E9.5

craniofacial

small pharyngeal arch ( J:262499 )

• at E9.5