Phenotypes Associated with This Genotype

Genotype
MGI:6163711

• Allelic Composition: Adam10^Pied/Adam10⁺; Hr^hr/Hr^hr
• Genetic Background: HRA/SkhKcl-Adam10^Pied Hr^Hr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

hairless ( J:262499 )

abnormal skin pigmentation ( J:262499 )

• unlike in Hr^Hr homozygotes, 20 week old mice exhibit light brown, freckle-like spots or macules with a striated appearance due to a heavier concentration of melanin at the dermis and epidermis junction

• at 10 months, mice exhibit un-striated macules in the tail, ear and feet that does not change skin color unlike in Hr^Hr homozygotes

pigmentation

abnormal skin pigmentation ( J:262499 )

• unlike in Hr^Hr homozygotes, 20 week old mice exhibit light brown, freckle-like spots or macules with a striated appearance due to a heavier concentration of melanin at the dermis and epidermis junction

• at 10 months, mice exhibit un-striated macules in the tail, ear and feet that does not change skin color unlike in Hr^Hr homozygotes