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Phenotypes Associated with This Genotype
Genotype
MGI:6159582
Allelic
Composition		 Map2k1tm2.1Chrn/Map2k1tm1.1Chrn
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map2k1tm1.1Chrn mutation (0 available); any Map2k1 mutation (95 available)
Map2k1tm2.1Chrn mutation (1 available); any Map2k1 mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
pulmonary artery stenosis ( J:261678 )
• pulmonary artery stenosis is observed at E13.5
• left and right pulmonary artery lumen areas are reduced

craniofacial

skeleton

vision/eye
increased inner canthal distance ( J:261678 )
• width of the inner canthal distance is increased

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory