About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6157644
Allelic
Composition		 Notch2tm2.1Ecan/Notch2tm2.1Ecan
Lyz2tm1(cre)Ifo/Lyz2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyz2tm1(cre)Ifo mutation (16 available); any Lyz2 mutation (42 available)
Notch2tm2.1Ecan mutation (0 available); any Notch2 mutation (97 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
skeleton phenotype ( J:246017 )
N
• femoral microarchitecture is normal at 1 and 4 months of age and bone marrow-derived macrophage cultures form a similar number of osteoclasts in vitro as controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory