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Phenotypes Associated with This Genotype
Genotype
MGI:6151074
Allelic
Composition
Slc29a1tm2Msg/Slc29a1tm2Msg
Eportm1.1(EGFP/icre)Uk/Epor+
Genetic
Background
involves: 129X1/SvJ * BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eportm1.1(EGFP/icre)Uk mutation (2 available); any Epor mutation (25 available)
Slc29a1tm2Msg mutation (0 available); any Slc29a1 mutation (40 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• under acute hypoxic conditions, mice exhibit a faster increase in serum adenosine levels than in wild-type mice
• under acute hypoxic conditions, mice exhibit reduced tissue hypoxia in the heart, kidney and lung with reduced total cell numbers, albumin and IL6 concentration bronchoalveolar lavage fluid, pulmonary myeloperoxidase activity, and perivascular edema compared with wild-type mice

immune system
• in the lungs of mice exposed to hypoxic conditions


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory