Phenotypes Associated with This Genotype

Genotype
MGI:6150434

• Allelic Composition: Tg(Mnx1-Zfp106,-EGFP)2Blk/0; Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi}
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0033_4_C03

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal muscle fiber morphology ( J:241305 )

• significant suppression of muscle wasting compared to Zfp106 knockout allele alone

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:241305 )

• significant suppression of muscle wasting and of loss of grip strength compared to Zfp106 knockout allele alone

nervous system

abnormal motor neuron morphology ( J:241305 )

• significant restoration of number of choline-acetyltransferase-positive motor neurons in spinal cord compared to Zfp106 knockout allele alone

growth/size/body

abnormal body weight ( J:241305 )

• significant suppression of muscle wasting compared to Zfp106 knockout allele alone