Phenotypes Associated with This Genotype

Genotype
MGI:6121073

• Allelic Composition: Dstyk^tm1.2Zlh/Dstyk^tm1.2Zlh
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:226871 )

N • no locomotion deficits in the open field and rotarod tests

N • average swimming speed during Morris water maze test

impaired spatial learning ( J:226871 )

• time spent to swim to target platform significantly longer during trials 3 and 4 of Morris water maze test with visible platform

• latency to target platform was significantly higher during Morris water maze test with hidden platform

• number of target platform crossings, time spent in target quadrant and relative total distance moved during Morris water maze test with hidden platform

nervous system

nervous system phenotype ( J:226871 )

N • no obvious brain morphological abnormalities