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Phenotypes Associated with This Genotype
Genotype
MGI:6118906
Allelic
Composition		 H2-D1b-em4Dvs/H2-D1b-em4Dvs
Genetic
Background		 NOD/ShiLtDvs-H2-D1b-em4Dvs/Dvs
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2-D1b-em4Dvs mutation (2 available); any H2-D1 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to autoimmune diabetes ( J:257229 )
• insulitis is decreased at 10-15 weeks of age and diabetes onset is delayed and less severe, but not ablated, relative to wild-type controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory