Phenotypes for Rimbp2 Tspoap1 MGI:6117378 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rimbp2^tm1.2Geno/Rimbp2^tm1.2Geno Tspoap1^tm1.2Geno/Tspoap1^tm1.2Geno
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rimbp2^tm1.2Geno mutation (0 available); any Rimbp2 mutation (49 available)
Tspoap1^tm1.2Geno mutation (0 available); any Tspoap1 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:238503 )

N	• excitatory postsynaptic potential at different volley amplitudes in acute hippocampal slices

abnormal synaptic plasticity ( J:238503 )

abnormal CNS synaptic transmission ( J:238503 )

• increased paired-pulse ratio for all inter-stimulus intervals tested in acute hippocampal slices

enhanced paired-pulse facilitation ( J:238503 )

• increased after train stimulations with 25 pulses at 14 Hz in acute hippocampal slices

abnormal paired-pulse inhibition ( J:238503 )

• reduced after train stimulations with 25 pulses at 14 Hz in acute hippocampal slices

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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