Tspoap1^tm1.2Geno
Targeted Allele Detail

Summary

• Symbol: Tspoap1^tm1.2Geno
• Name: TSPO associated protein 1; targeted mutation 1.2, Genoway
• MGI ID: MGI:6116838
• Synonyms: RIM-BP1 KO
• Gene: Tspoap1 Location: Chr11:87651367-87676754 bp, + strand Genetic Position: Chr11, 52.21 cM
• Alliance: Tspoap1^tm1.2Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238503
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A LoxP site and an FRT-flanked neomycin resistance cassette were inserted into intron 22 and a second loxP site into intron 25. The neo cassette was removed through flp-mediated recombination and exons 23-25 were deleted through cre-mediated recombination. (J:238503)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspoap1 Mutation: 50 strains or lines available

References

• Original: J:238503 Grauel MK, et al., RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11615-11620
• All: 1 reference(s)