About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6106901
Allelic
Composition		 Nr1h3tm1Djm/Nr1h3tm1Djm
Nus1tm1.1Qrm/Nus1tm1.1Qrm
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background		 involves: 129 * C57BL/6 * DBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr1h3tm1Djm mutation (3 available); any Nr1h3 mutation (32 available)
Nus1tm1.1Qrm mutation (0 available); any Nus1 mutation (16 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:243753 )
N
• when fed Western diet
• circulating triglyceride level
• liver triglyceride level
• circulating free fatty acid level
• liver free fatty acid level
• circulating cholesterol level both total and free
increased liver cholesterol level ( J:243753 )
• both total and free when fed Western diet

liver/biliary system
increased liver cholesterol level ( J:243753 )
• both total and free when fed Western diet

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory