Phenotypes Associated with This Genotype

Genotype
MGI:6106900

• Allelic Composition: Nus1^tm1.1Qrm/Nus1^tm1.1Qrm; Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
• Genetic Background: involves: 129 * C57BL/6 * DBA * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal lipid homeostasis ( J:243753 )

♀ • induction of hepatic lipogenesis when fed Western diet

abnormal circulating cholesterol level ( J:243753 )

♀ • both total and free when fed Western diet

increased circulating free fatty acids level ( J:243753 )

♀ • when fed Western diet

increased circulating triglyceride level ( J:243753 )

♀ • when fed Western diet

decreased liver cholesterol level ( J:243753 )

♀ • both total and free when fed Western diet

increased liver free fatty acids level ( J:243753 )

♀ • when fed Western diet

increased liver triglyceride level ( J:243753 )

♀ • when fed Western diet

liver/biliary system

decreased liver cholesterol level ( J:243753 )

♀ • both total and free when fed Western diet

increased liver free fatty acids level ( J:243753 )

♀ • when fed Western diet

increased liver triglyceride level ( J:243753 )

♀ • when fed Western diet