Phenotypes for Acsl1 Tg(Fabp4-cre)1Rev MGI:6103877 MGI Mouse

decreased fatty acid oxidation ( J:162996 )

• in white adipose tissue

impaired adaptive thermogenesis ( J:162996 )

• in cold exposed mice due to decreased fatty acid oxidation

hypoglycemia ( J:162996 )

• during cold exposure

• after adrenergic stimuli with isoproterenol or CL-316243

• however, glucose levels are normal after fasting

• in response to CL-316243 due to reduced glycerol release by brown adipocytes

hyperlipidemia ( J:162996 )

• after adrenergic stimuli

increased fatty acids level ( J:162996 )

• in white adipose tissue when fed a low-fat diet with different fatty acid species

• after cold exposure or CL-316243 treatment

• however, fasting does not abnormally increase fatty acid levels

increased triglyceride level ( J:162996 )

• with increased diacylglycerol level in white adipose tissue when fed a low-fat diet

• after cold exposure

• when fed a low-fat diet

increased body fat mass ( J:162996 )

• when fed a 10% fat diet

• however, mice fed a high-fat diet exhibit normal weight gain and adipocity

• when fed a low-fat diet

• however, mice fed a high-fat diet exhibit lipid levels

increased gonadal fat pad weight ( J:162996 )

• when fed a 10% fat diet or chow

• however, adipocyte size is normal

increased body fat mass ( J:162996 )

• when fed a 10% fat diet

• however, mice fed a high-fat diet exhibit normal weight gain and adipocity

decreased fatty acid oxidation ( J:162996 )

• in white adipose tissue

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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