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Phenotypes Associated with This Genotype
Genotype
MGI:6098759
Allelic
Composition		 Chattm2(cre)Lowl/Chat+
Mecp2tm2Bird/Y
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chattm2(cre)Lowl mutation (4 available); any Chat mutation (63 available)
Mecp2tm2Bird mutation (1 available); any Mecp2 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
abnormal respiration ( J:241788 )
• abnormal hypoxic breathing response

behavior/neurological
behavior/neurological phenotype ( J:241788 )
N
• mice exhibit normal activity

cardiovascular system
cardiovascular system phenotype ( J:241788 )
N
• mice exhibit a regular heart rate and show rescue of spontaneous and induced cardiac arrhythmias, long QT, and improved survival

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:241788 )
N
• mice exhibit a regular body temperature

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory