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Phenotypes Associated with This Genotype
Genotype
MGI:5912010
Allelic
Composition		 Pkn2tm1c(KOMP)Wtsi/Pkn2tm1c(KOMP)Wtsi
Tg(Tagln-cre)1Jjl/0
Genetic
Background		 involves: C57BL/6N * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkn2tm1c(KOMP)Wtsi mutation (0 available); any Pkn2 mutation (84 available)
Tg(Tagln-cre)1Jjl mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
cardiac hypertrophy ( J:229595 )
• in survivors

respiratory system
overexpanded pulmonary alveolus ( J:229595 )
• alveolar enlargement in survivors
pulmonary fibrosis ( J:229595 )
• in survivors

growth/size/body
cardiac hypertrophy ( J:229595 )
• in survivors

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory