Phenotypes for Cd19 Rnaseh2b MGI:5911410 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rnaseh2b^{tm1c(EUCOMM)Wtsi}/Rnaseh2b^{tm1c(EUCOMM)Wtsi} Cd19^tm1(cre)Cgn/Cd19⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
Cell Lines	EPD0087_4_A02

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19^tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
Rnaseh2b^{tm1c(EUCOMM)Wtsi} mutation (0 available); any Rnaseh2b mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:186986 )

N	• mice exhibit normal numbers of B cells in the spleen

decreased B cell proliferation ( J:186986 )

• LPS-induced

hematopoietic system

decreased B cell proliferation ( J:186986 )

• LPS-induced

cellular

decreased B cell proliferation ( J:186986 )

• LPS-induced

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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