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Phenotypes Associated with This Genotype
Genotype
MGI:5907496
Allelic
Composition		 Mcm3tm1.1Geno/Mcm3tm1.1Geno
Tg(Chek1)1Ofc/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm3tm1.1Geno mutation (0 available); any Mcm3 mutation (41 available)
Tg(Chek1)1Ofc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:227638 )
• partial rescue of the prenatal lethality (7.6% compared to the expected 12.5%)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory