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Phenotypes Associated with This Genotype
Genotype
MGI:5902584
Allelic
Composition		 Foxf1tm1.1Vvk/Foxf1tm1.1Vvk
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxf1tm1.1Vvk mutation (0 available); any Foxf1 mutation (14 available)
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased vascular endothelial cell number ( J:240455 )
• in lungs of E17.5 embryos after tamoxifen exposure of the mothers
abnormal vascular branching morphogenesis ( J:240455 )
• reduced branching in placenta and yolk sac in E12.5 embryos 3 days after tamoxifen exposure of the mothers
decreased angiogenesis ( J:240455 )
• in retina of P6.5 pups after tamoxifen exposure at P0, P1 and P2

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory