Phenotypes Associated with This Genotype

Genotype
MGI:5898010

• Allelic Composition: Ino80^tm1.1Schg/Ino80^tm1.1Schg
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

embryonic growth retardation ( J:221224 )

• all E7.5-E8.5 embryos exhibit severe growth retardation

mortality/aging

embryonic lethality, incomplete penetrance ( J:221224 )

• between E7.5-E10.5 the fraction of embryos was below the expected Mendelian ratio

• by E13.5-E14.5 the majority of embryos were resorbed

preweaning lethality, complete penetrance ( J:221224 )

• by P21 no embryos survived

embryo

abnormal embryo development ( J:221224 )

• all E7.5-E8.5 embryos exhibit intrauterine developmental abnormalities

embryonic growth retardation ( J:221224 )

• all E7.5-E8.5 embryos exhibit severe growth retardation