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Phenotypes Associated with This Genotype
Genotype
MGI:5897856
Allelic
Composition		 Braftm1Mmcm/Braf+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Braftm1Mmcm mutation (4 available); any Braf mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
increased thyroid carcinoma incidence ( J:208854 )
• mice with surgical delivery of a cre-expressing adenovirus to the adult thyroid gland develop papillary thyroid carcinoma

neoplasm
increased thyroid carcinoma incidence ( J:208854 )
• mice with surgical delivery of a cre-expressing adenovirus to the adult thyroid gland develop papillary thyroid carcinoma

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory