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Phenotypes Associated with This Genotype
Genotype
MGI:5882547
Allelic
Composition		 Fgfr1tm5.1Sor/Fgfr1tm10.1Sor
Stat3tm2Aki/Stat3tm2Aki
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr1tm10.1Sor mutation (1 available); any Fgfr1 mutation (219 available)
Fgfr1tm5.1Sor mutation (0 available); any Fgfr1 mutation (219 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
Stat3tm2Aki mutation (1 available); any Stat3 mutation (72 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
craniofacial phenotype ( J:226497 )
N
• none of the 4 mice examined exhibit cleft palate, likely due to the low penetrance of cleft palate found in Fgfr1tm5.1Sor/Fgfr1tm10.1Sor mice (2 of 13)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory