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Phenotypes Associated with This Genotype
Genotype
MGI:5881916
Allelic
Composition		 ApcMin/Apc+
Spata13tm1Taki/Spata13tm1Taki
Genetic
Background		 B6J.Cg-Spata13tm1Taki ApcMin
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (151 available)
Spata13tm1Taki mutation (0 available); any Spata13 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal survival ( J:157023 )
• mice survive significantly longer than ApcMin heterozygotes

neoplasm
decreased intestinal adenoma incidence ( J:157023 )
• at 4 months of age, mice show an even greater reduction in the total number of intestinal adenomas (polyps) per mouse than mice that are homozygous for Arhgef4tm1Taki and heterozygous for ApcMin
decreased tumor growth/size ( J:157023 )
• at 4 months of age, mice show an even greater reduction in the size of intestinal adenomas (polyps) than mice that are homozygous for Arhgef4tm1Taki and heterozygous for ApcMin

digestive/alimentary system
decreased intestinal adenoma incidence ( J:157023 )
• at 4 months of age, mice show an even greater reduction in the total number of intestinal adenomas (polyps) per mouse than mice that are homozygous for Arhgef4tm1Taki and heterozygous for ApcMin

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory