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Phenotypes Associated with This Genotype
Genotype
MGI:5829559
Allelic
Composition		 Hnrnputm1.1Tman/Hnrnputm1.1Tman
Tg(Myh6-cre)2182Mds/0
Genetic
Background		 involves: 129S4/SvJaeSor * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hnrnputm1.1Tman mutation (1 available); any Hnrnpu mutation (43 available)
Tg(Myh6-cre)2182Mds mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:223139 )
• although born at normal Mendelian ratios, all mice die abruptly from heart failure at exactly 10 days after birth

cardiovascular system
dilated cardiomyopathy ( J:223139 )
• mice develop severe, lethal dilated cardiomyopathy

muscle
dilated cardiomyopathy ( J:223139 )
• mice develop severe, lethal dilated cardiomyopathy

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory