Phenotypes Associated with This Genotype

Genotype
MGI:5827855

• Allelic Composition: Cacfd1^tm1Lex/Cacfd1^tm1Lex
• Genetic Background: B6;129S5-Cacfd1^tm1Lex/Mmucd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased startle reflex ( J:171883 )

• homozygous mutant mice failed to startle during prepulse inhibition testing, suggestive of a possible hearing impairment

homeostasis/metabolism

increased circulating cholesterol level ( J:171883 )

♂

increased circulating triglyceride level ( J:171883 )

• male and female homozygous mutant mice exhibited increased serum triglyceride levels, the difference being more notable in the females