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Phenotypes Associated with This Genotype
Genotype
MGI:5824896
Allelic
Composition		 Mapk14tm1.1Otsu/Mapk14tm1.2Otsu
Slc6a3tm1(cre)Xz/0
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapk14tm1.1Otsu mutation (0 available); any Mapk14 mutation (43 available)
Mapk14tm1.2Otsu mutation (1 available); any Mapk14 mutation (43 available)
Slc6a3tm1(cre)Xz mutation (2 available); any Slc6a3 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:226396 )
N
• performance on the rotarod is similar to controls, although there is a slight trend toward improved performance
abnormal associative learning ( J:226396 )
• resistant to agonist U50,488-induced conditioned place aversion (CPA)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory