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Phenotypes Associated with This Genotype
Genotype
MGI:5824303
Allelic
Composition		 Wt1tm1.1Ndha/Wt1tm1.1Ndha
Tg(Tek-cre/ERT2)1Arnd/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Tek-cre/ERT2)1Arnd mutation (1 available)
Wt1tm1.1Ndha mutation (0 available); any Wt1 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal coronary vessel morphology ( J:229936 )
• embryos from pregnant females injected with tamoxifen at E10 show a reduction in the number of coronary vessels, especially transmural vessels connecting endocardial and epicardial elements of the coronary vasculature
• however, mice injected with tamoxifen at E10 show normal heart morphology

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory