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Phenotypes Associated with This Genotype
Genotype
MGI:5819213
Allelic
Composition		 a/a
Tyrc/Tyrem2Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (166 available); any a mutation (468 available)
Tyrc mutation (79 available); any Tyr mutation (382 available)
Tyrem2Ove mutation (1 available); any Tyr mutation (382 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:94077 )
• on a nonagouti background, the fur of these compound Tyr heterozygotes appears lighter gray than that of mice homozygous for Tyrem2Ove

pigmentation
diluted coat color ( J:94077 )
• on a nonagouti background, the fur of these compound Tyr heterozygotes appears lighter gray than that of mice homozygous for Tyrem2Ove
decreased eye pigmentation ( J:94077 )
• these mice exhibit lighter ocular pigmentation than Tyrem2Ove homozygotes

vision/eye
decreased eye pigmentation ( J:94077 )
• these mice exhibit lighter ocular pigmentation than Tyrem2Ove homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory