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Phenotypes Associated with This Genotype
Genotype
MGI:5817582
Allelic
Composition
a/a
Tyrem2Ove/Tyrem2Ove
Genetic
Background
involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (166 available); any a mutation (468 available)
Tyrem2Ove mutation (1 available); any Tyr mutation (382 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• the tails of these mice are lightly pigmented

vision/eye
• these mice exhibit altered ocular pigmentation compared to wild-type mice

integument
• mice homozygous for this tyrosinase promoter mutation on a nonagouti background appear light gray
• the tails of these mice are lightly pigmented

pigmentation
• mice homozygous for this tyrosinase promoter mutation on a nonagouti background appear light gray
• the tails of these mice are lightly pigmented
• these mice exhibit altered ocular pigmentation compared to wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory