Phenotypes for Gt(ROSA)26Sor Lep Tg(Adipoq-cre)1Evdr MGI:5816452 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm1(Notch1)Dam}/Gt(ROSA)26Sor⁺ Lep^ob/Lep^ob Tg(Adipoq-cre)1Evdr/0
Genetic Background	involves: 129S4/SvJaeSor * C57BL/6J * FVB/NJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(Notch1)Dam} mutation (1 available); any Gt(ROSA)26Sor mutation (1062 available)
Lep^ob mutation (5 available); any Lep mutation (19 available)
Tg(Adipoq-cre)1Evdr mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

adipose tissue phenotype ( J:237232 )

N	• mice show normalization of obesity phenotype seen in single Lep^ob homozygotes

homeostasis/metabolism

hyperglycemia ( J:237232 )

• mice exhibit very high blood glucose levels

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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