Phenotypes Associated with This Genotype

Genotype
MGI:5806227

• Allelic Composition: Ica1l^em1Jxia/Ica1l^em1Jxia
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal sperm mitochondrial sheath morphology ( J:233657 )

♂

oligozoospermia ( J:233657 )

♂ • in the cauda epididymis

♂ • reduced mobile and linear mobile sperm form the cauda epididymis

abnormal sperm nucleus morphology ( J:233657 )

♂ • smaller and irregular compared with wild-type sperm

abnormal spermiogenesis ( J:233657 )

♂ • with round nuclei sperm

globozoospermia ( J:233657 )

♂

decreased litter size ( J:233657 )

♂ • reduced litter size produced from male mice

reduced male fertility ( J:233657 )

♂ • with reduced litter size

cellular

abnormal sperm mitochondrial sheath morphology ( J:233657 )

♂

oligozoospermia ( J:233657 )

♂ • in the cauda epididymis

♂ • reduced mobile and linear mobile sperm form the cauda epididymis

globozoospermia ( J:233657 )

♂

abnormal sperm nucleus morphology ( J:233657 )

♂ • smaller and irregular compared with wild-type sperm