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Phenotypes Associated with This Genotype
Genotype
MGI:5780069
Allelic
Composition		 Kmt2dtm1.1Kaig/Kmt2d+
Cd19tm1(cre)Cgn/Cd19+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
Kmt2dtm1.1Kaig mutation (1 available); any Kmt2d mutation (169 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased germinal center B cell number ( J:228913 )
• intermediate at 3 and 6 months in mice immunized with sheep red blood cell
increased spleen germinal center size ( J:228913 )
• intermediate at 3 and 6 months in mice immunized with sheep red blood cell

hematopoietic system
increased germinal center B cell number ( J:228913 )
• intermediate at 3 and 6 months in mice immunized with sheep red blood cell
increased spleen germinal center size ( J:228913 )
• intermediate at 3 and 6 months in mice immunized with sheep red blood cell

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory