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Phenotypes Associated with This Genotype
Genotype
MGI:5763152
Allelic
Composition		 Smg6tm1.2Zqw/Smg6tm1.2Zqw
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smg6tm1.2Zqw mutation (0 available); any Smg6 mutation (97 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:222980 )
• no viable mice are produced

embryo
decreased inner cell mass proliferation ( J:222980 )
• cultured blastocysts fail to grown
embryonic growth retardation ( J:222980 )
• rare embryos are growth retarded at E7.5

growth/size/body
embryonic growth retardation ( J:222980 )
• rare embryos are growth retarded at E7.5

cellular
decreased inner cell mass proliferation ( J:222980 )
• cultured blastocysts fail to grown

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory