Phenotypes Associated with This Genotype

Genotype
MGI:5757834

• Allelic Composition: Ttc28^{tm1b(EUCOMM)Hmgu}/Ttc28^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Ttc28^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0680_1_C11

Data Sources

IMPC Data for Ttc28

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

IMPC - TCP

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - TCP

abnormal maxilla morphology ( J:211773 )

IMPC - TCP

abnormal zygomatic bone morphology ( J:211773 )

IMPC - TCP

growth/size/body

abnormal maxilla morphology ( J:211773 )

IMPC - TCP

abnormal zygomatic bone morphology ( J:211773 )

IMPC - TCP

decreased body length ( J:211773 )

IMPC - TCP

hematopoietic system

increased red blood cell distribution width ( J:211773 )

♂

IMPC - TCP

increased leukocyte cell number ( J:211773 )

♀

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - TCP

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - TCP

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - TCP

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♀

IMPC - TCP

nervous system

decreased prepulse inhibition ( J:211773 )

♂

IMPC - TCP

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - TCP

abnormal maxilla morphology ( J:211773 )

IMPC - TCP

abnormal zygomatic bone morphology ( J:211773 )

IMPC - TCP

short tibia ( J:211773 )

IMPC - TCP

abnormal pelvic girdle bone morphology ( J:211773 )

IMPC - TCP

abnormal vertebrae morphology ( J:211773 )

IMPC - TCP

vertebral fusion ( J:211773 )

IMPC - TCP

decreased bone mineral density ( J:211773 )

♀

IMPC - TCP