Phenotypes Associated with This Genotype

Genotype
MGI:5757742

• Allelic Composition: Smoc1^{tm1b(EUCOMM)Wtsi}/Smoc1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Smoc1^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0348_1_C03

Data Sources

IMPC Data for Smoc1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired pupillary reflex ( J:211773 )

♀

IMPC - HAR

abnormal gait ( J:211773 )

IMPC - HAR

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - HAR

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HAR

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - HAR

abnormal maxilla morphology ( J:211773 )

IMPC - HAR

abnormal snout morphology ( J:211773 )

IMPC - HAR

growth/size/body

abnormal maxilla morphology ( J:211773 )

IMPC - HAR

abnormal snout morphology ( J:211773 )

IMPC - HAR

abnormal head size ( J:211773 )

♀

IMPC - HAR

hematopoietic system

increased neutrophil cell number ( J:211773 )

♀

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

immune system

increased neutrophil cell number ( J:211773 )

♀

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

limbs/digits/tail

abnormal digit morphology ( J:211773 )

IMPC - HAR

syndactyly ( J:211773 )

IMPC - HAR

short tibia ( J:211773 )

♀

IMPC - HAR

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - HAR

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - HAR

abnormal maxilla morphology ( J:211773 )

IMPC - HAR

short tibia ( J:211773 )

♀

IMPC - HAR

abnormal pelvic girdle bone morphology ( J:211773 )

♀

IMPC - HAR

vision/eye

impaired pupillary reflex ( J:211773 )

♀

IMPC - HAR

abnormal optic disk morphology ( J:211773 )

IMPC - HAR

mydriasis ( J:211773 )

♀

IMPC - HAR

narrow eye opening ( J:211773 )

♀

IMPC - HAR

abnormal retina morphology ( J:211773 )

♂

IMPC - HAR

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - HAR

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HAR